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Start with the family. An OMEN panel is specified around motion: high refresh rates, validated adaptive sync and, at the top of the range, a QD-OLED with per-pixel light output. A Series 5 screen is specified around a desk: slim bezels, low-blue-light hardware and a refresh rate that lifts scrolling above 60Hz without asking anything of the graphics card.
Then match the panel to what is driving it. A 240Hz QHD screen only earns its price if the machine behind it produces frames at that rate in the games you play, and an ultrawide needs both the desk depth and the graphics card to fill 3440 x 1440. Where the screen doubles as a work display, connectivity and stand travel matter more than another 60Hz.