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Begin with the pairing that decides how the whole setup feels. A tower capable of high frame rates sitting behind a 60Hz panel feels no quicker than a far cheaper one, and a 4K screen in front of entry-level graphics forces settings down until the picture ends up worse than it would have been at a lower resolution. Resolution and refresh rate are the two figures to fix first, with everything else arranged behind them.
Then account for what has quietly been left out. An operating system licence, a second display lead if two screens are planned, and any form of sound are the omissions that surface on the evening you set the machine up rather than at checkout. None is expensive on its own. Finding all three absent at once is what turns a good buy into an irritating one.